Case Study

A case report of chondroblastic osteosarcoma following treatment for Hodgkin lymphoma

Tenille A. Abrahams, Farah Rahman, Sharlene Parasnath
South African Journal of Oncology | Vol 8 | a310 | DOI: https://doi.org/10.4102/sajo.v8i0.310 | © 2024 Tenille A. Abrahams, Farah Rahman, Sharlene Parasnath | This work is licensed under CC Attribution 4.0
Submitted: 25 July 2024 | Published: 30 November 2024

About the author(s)

Tenille A. Abrahams, Department of Clinical Haematology, Faculty of Clinical Medicine, Inkosi Albert Luthuli Central Hospital, Durban, South Africa
Farah Rahman, Department of Clinical Haematology, Faculty of Clinical Medicine, Inkosi Albert Luthuli Central Hospital, Durban, South Africa; and Department of Clinical Haematology, Discipline of Internal Medicine, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa
Sharlene Parasnath, Department of Clinical Haematology, Faculty of Clinical Medicine, Inkosi Albert Luthuli Central Hospital, Durban, South Africa; and Department of Clinical Haematology, Discipline of Internal Medicine, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa

Abstract

Patients diagnosed with Hodgkin lymphoma (HL) have improved survival because of the early use of effective therapies and positron emission tomography (PET) – adapted strategies. However, long-term observational studies have shown that HL survivors have an increased risk of secondary cancers and other complications, which include cardiovascular disease, infertility and endocrinopathies. Therefore, long-term follow-up and screening of HL survivors is important.

Contribution: We report a case of a 22-year-old female with chondroblastic osteosarcoma following treatment of HL. We have devised a simple screening algorithm to ensure comprehensive long-term surveillance of HL survivors.


Keywords

Hodgkin lymphoma; osteosarcoma; radiotherapy; mandible mass; secondary malignancy

Sustainable Development Goal

Goal 3: Good health and well-being

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