Case Study

A rare presentation of bilateral synchronous renal tumours misdiagnosed as tuberculosis

Debi M. Moagi, Busiswa F. Bisiwe
South African Journal of Oncology | Vol 9 | a311 | DOI: https://doi.org/10.4102/sajo.v9i0.311 | © 2025 Debi M. Moagi, Busiswa F. Bisiwe | This work is licensed under CC Attribution 4.0
Submitted: 02 September 2024 | Published: 28 February 2025

About the author(s)

Debi M. Moagi, Department of Internal Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa
Busiswa F. Bisiwe, Division of Nephrology, Department of Internal Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa

Abstract

A 32-year-old woman with dialysis-requiring kidney failure presented with constitutional symptoms and bilateral kidney masses and was initially diagnosed with renal tuberculosis (TB). However, despite TB treatment, her condition deteriorated, leading to a right nephrectomy. Histopathological examination revealed the presence of embryonal rhabdomyosarcoma (ERMS), a rare malignancy typically seen in paediatric populations. Alternative diagnoses, even rare ones like ERMS, should be considered when dealing with bilateral kidney masses. Radical nephrectomy remains the primary treatment for ERMS, but adjuvant therapies may also be beneficial.

Contribution: This case highlights the diagnostic challenges of bilateral kidney masses and the importance of considering rare malignancies in the differential diagnosis. Prompt histopathological evaluation is crucial for accurate diagnosis and timely management.


Keywords

kidney masses; tuberculosis; embryonal rhabdomyosarcoma; misdiagnosis; diagnostic challenges

Sustainable Development Goal

Goal 3: Good health and well-being

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